Posted by: cancervisa | November 16, 2008

metatasis breast cancer

New Metastatic Programs Just for You!
Every 4th Tuesday of the month at 8:00 p.m.(ET)/ 5:00p.m.(PT) join the YSC for special one-hour interactive calls with medical updates on advanced breast cancer, inspirational talks featuring renowned health care professionals and survivor advocate stories!  Join us on Tuesday, November 25th when the call will feature Robert Vahary, MSW, providing guidance and tips on Mindful Living, Meditative Practices, and Health as we head into the oftentimes stressful holiday season. Please rsvp to ywabc@youngsurvival.org to receive dial-in information for this call

Posted by: cancervisa | November 16, 2008

cancer on radio

Matthew Zachary, The Stupid Cancer Show is a pioneering new interactive talk radio broadcast finally giving voice to more than one million young adults affected by cancer. The Stupid Cancer Show show airs live every Monday at 9:00 p.m. (ET) / 6:00 p.m. (PT) with special guests from all areas of the cancer continuum, including young adult advocates (AYA), survivors, musicians, authors, bloggers, oncology gurus and organizational leaders. Register and learn more at The Stupid Cancer Show website.

Posted by: cancervisa | November 6, 2008

Cancer genetic blueprint for the first time

Leukaemia cells
Scientists say they have worked out the complete genetic blueprint of a cancer for the first time.
Posted by: cancervisa | November 5, 2008

Michael Crichton dies of cancer

AP

In this Dec. 7, 2004 file photo, author Michael Crichton poses at The Peninsula AP – In this Dec. 7, 2004 file photo, author Michael Crichton poses at The Peninsula Hotel in New York. Crichton …

NEW YORK – The family of Michael Crichton, the million-selling author of such historic and prehistoric science fantasies as “Jurassic Park,” “Timeline” and “The Andromeda Strain,” says the author has died in Los Angeles.

Crichton died Tuesday at age 66. He had been privately battling cancer, his family said.

“Through his books, Michael Crichton served as an inspiration to students of all ages, challenged scientists in many fields, and illuminated the mysteries of the world in a way we could all understand,” his family said in a statement.

 

Posted by: cancervisa | November 3, 2008

eye test that can tell me if my kid will have cancer for 399$?

it’s that cool.

2. The Tesla Roadster – A 125 mph electric car. Definitely want.

1. The Retail DNA Test (Picture right) –  For $399 you can find out what your risks are for developing genetic-based diseases — and how your hypothetical children might fare, as well. I’m deeply afraid of these tests because I’m already totally paranoid about my health as it is. I badly bruised my foot this week and a little web searching had me convinced it was a life-threatening brown recluse spider bit. Do I really need my genes telling me I have an 80 percent chance of Alzheimer’s? Yikes. Still, very cool idea and finally affordable.

WASHINGTON – Someone in your house have the sniffles? Watch out for the refrigerator door handle. The TV remote, too. A new study finds that cold sufferers often leave their germs there, where they can live for two days or longer.

Scientists at the University of Virginia, long known for its virology research, tested surfaces in the homes of people with colds and reported the results Tuesday at the nation’s premier conference on infectious diseases.

Doctors don’t know how often people catch colds from touching germy surfaces as opposed to, say, shaking a sick person’s hand, said Dr. Birgit Winther, an ear, nose and throat specialist who helped conduct the study.

Two years ago, she and other doctors showed that germs survived in hotel rooms a day after guests left, waiting to be picked up by the next person checking in.

For the new study, researchers started with 30 adults showing early symptoms of colds. Sixteen tested positive for rhinovirus, which causes about half of all colds. They were asked to name 10 places in their homes they had touched in the preceding 18 hours, and researchers used DNA tests to hunt for rhinovirus.

“We found that commonly touched areas like refrigerator doors and handles were positive about 40 percent of the time” for cold germs, Winther said.

All three of the salt and pepper shakers they tested were contaminated. Other spots found to harbor the germ: 6 out of 18 doorknobs; 8 of 14 refrigerator handles; 3 of 13 light switches; 6 of 10 remote controls; 8 of 10 bathroom faucets; 4 of 7 phones, and 3 of 4 dishwasher handles.

Next, the researchers deliberately contaminated surfaces with participants’ mucus and then tested to see whether rhinovirus stuck to their fingers when they turned on lights, answered the phone or did other common tasks. More than half of the participants got the virus on their fingertips 48 hours after the mucus was smeared.

The study was sponsored by Reckitt-Benckiser Inc., makers of Lysol, but no products were tested in the research. The study, designed by doctors with no ties to the company, was an effort to lay the groundwork for future research on germs and ways to get rid of them.

In a separate study, the university’s Drs. Diane Pappas and Owen Hendley went germ-hunting on toys in the offices of five pediatricians in Fairfax, Va., three times during last year’s cold and flu season.

Tests showed fragments of cold viruses on 20 percent of all toys tested — 20 percent of those in the “sick child” waiting room, 17 percent in the “well child” waiting room, and 30 percent in a sack of toys that kids are allowed to choose from after being good for a shot.

“Mamas know this,” Hendley said. “They say, `We go to a doctor for a well-child checkup, the kids play with the toys and two days later they have a cold.'”

There is no proof that the remnants themselves can infect, but their presence suggests a risk, said Dr. Paul Auwaerter, an infectious-diseases specialist at Johns Hopkins University. He was familiar with the study but had no role in it.

Doctors have long advised frequent hand-washing to avoid spreading germs. Wearing surgical masks and using hand sanitizers also can help, a novel University of Michigan study found.

About 1,000 students who live in dorms tested these measures for six weeks during the 2006-07 flu season. They were divided into three groups: those who wore masks, those who wore masks and used hand sanitizer, and those who did neither.

The two groups who used masks reported 10 percent to 50 percent fewer cold symptoms — cough, fever, chills — than the group who used no prevention measures.

Researchers note that the study was not “blinded” — everyone knew who was doing what, and mask wearers may have been less likely to report cold symptoms later because they believed they were taking steps to reduce that possibility.

The federal Centers for Disease Control and Prevention paid for the study.

The conference was a joint meeting of the American Society for Microbiology and the Infectious Diseases Society of America.

___

On the Net:

Microbiology meeting: http://www.icaacidsa2008.org

Home hygiene advice: http://www.ifh-homehygiene.org/2003/2public/IFHrecomends.pdf

Posted by: cancervisa | October 30, 2008

nite sweatz and thumbs up for breast cancer

Hot Flashes, Night Sweats a Good Sign for Breast Cancer Patients

WEDNESDAY, Oct. 29 (HealthDay News) — Hot flashes, night sweats and joint symptoms in breast cancer patients getting endocrine treatment are signs of estrogen depletion or blockage and may point to successful treatment, British researchers report.

 

They compared women who reported these symptoms and those who didn’t mention such symptoms at their first follow-up visit during a trial assessing tamoxifen or anastrozole for adjuvant therapy of postmenopausal breast cancer.

 

The 37.5 percent of women who reported hot flashes and night sweats at the three-month follow-up visit had a lower breast cancer recurrence rate after nine years (18 percent) than women who didn’t report new vasomotor symptoms (23 percent). The 31.4 percent of women who reported new joint symptoms at the follow-up visit had a 14 percent rate of cancer recurrence, compared to 23 percent for those who didn’t report new joint symptoms.

 

The differences in cancer recurrence rates were seen with both tamoxifen and anastrozole. Overall, patients with and without these symptoms who received anastrozole had lower recurrence rates than those who received tamoxifen.

 

The study was published online and was expected to be in the December print issue of The Lancet Oncology.

 

“The appearance of new vasomotor symptoms or joint symptoms within the first three months is a useful biomarker, suggesting a greater response to endocrine treatment, compared with women without these symptoms,” wrote Professor Jack Cuzick, Cancer Research U.K. and Queen Mary School of Medicine and Dentistry, London, and colleagues.

 

“Awareness of the relation between early treatment-emergent symptoms and beneficial response to therapy might be useful when reassuring patients who present with them, and might help to improve long-term treatment adherence when symptoms cannot be alleviated,” Cuzick said in a news release from the journal.

 

More information

 

The National Cancer Institute has more about breast cancer treatment.

 

 

That’s a tricky question and, ultimately, each woman needs to make that decision with her doctor. But there are some advantages to having chemotherapy first.

Discuss
COMMENTS (0)

It may be a good option “in women who have a tumor that is too big in relation to the breast size for conservative surgery[lumpectomy] but who want to have conservative surgery,” said Dr. Eric Winer, director of breast cancer oncology at Dana-Farber Cancer Institute. In these cases, chemotherapy can often shrink a tumor enough to allow breast-conserving surgery. Women who get such surgery typically get radiation afterward to prevent local and regional recurrence.

If it’s clear, on the basis of various tests, that a woman is going to need chemotherapy regardless of what kind of surgery she has, having chemotherapy before surgery may also allow her to avoid radiation therapy, said Dr. Kuan Yu, an assistant professor of radiation oncology at M.D. Anderson Cancer Center in Houston. Yu is the lead author of a paper recently presented at a meeting of the American Society of Therapeutic Radiology and Oncology in Boston. Pre-op chemotherapy appears to allow a woman to skip radiation only if she has a mastectomy, not a lumpectomy, Yu said.

Although pre-op chemotherapy is increasingly being used, “there are still many unanswered questions” about it, said Winer. Some clinical trials routinely use pre-op chemotherapy. Whether or not a woman is in a clinical trial, he said, it’s crucial for her to discuss all the treatment options with her doctor, he said.

Judy Foreman

E-mail health questions to foreman@globe.com.

Posted by: cancervisa | October 29, 2008

Breast cancer and endocrine therapy and tumors

Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics.

Related Articles

Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics.

J Natl Cancer Inst. 2008 Oct 1;100(19):1380-8

Authors: Ellis MJ, Tao Y, Luo J, A’Hern R, Evans DB, Bhatnagar AS, Chaudri Ross HA, von Kameke A, Miller WR, Smith I, Eiermann W, Dowsett M

BACKGROUND: Understanding how tumor response is related to relapse risk would help clinicians make decisions about additional treatment options for patients who have received neoadjuvant endocrine treatment for estrogen receptor-positive (ER+) breast cancer. METHODS: Tumors from 228 postmenopausal women with confirmed ER+ stage 2 and 3 breast cancers in the P024 neoadjuvant endocrine therapy trial, which compared letrozole and tamoxifen for 4 months before surgery, were analyzed for posttreatment ER status, Ki67 proliferation index, histological grade, pathological tumor size, node status, and treatment response. Cox proportional hazards were used to identify factors associated with relapse-free survival (RFS) and breast cancer-specific survival (BCSS) in 158 women. A preoperative endocrine prognostic index (PEPI) for RFS was developed from these data and validated in an independent study of 203 postmenopausal women in the IMPACT trial, which compared treatment with anastrozole, tamoxifen, or the combination 3 months before surgery. Statistical tests were two-sided. RESULTS: Median follow-up in P024 was 61.2 months. Patients with confirmed baseline ER+ clinical stage 2 and 3 tumors that were downstaged to stage 1 or 0 at surgery had 100% RFS (compared with higher stages, P < .001). Multivariable testing of posttreatment tumor characteristics revealed that pathological tumor size, node status, Ki67 level, and ER status were independently associated with both RFS and BCSS. The PEPI model based on these factors predicted RFS in the IMPACT trial (P = .002). CONCLUSIONS: Breast cancer patients with pathological stage 1 or 0 disease after neoadjuvant endocrine therapy and a low-risk biomarker profile in the surgical specimen (PEPI score 0) have an extremely low risk of relapse and are therefore unlikely to benefit from adjuvant chemotherapy.

Posted by: cancervisa | October 29, 2008

Just had to talk with the shrink

I am feeling a bit lonely, and frankly I was at my wits end last week without help in my house and for my child. I have become quite spoiled and I have realized I can not take care of my child fully alone. Since this time I have had a very well needed vacation that has regenerated my batteries, and when the shrink showed up, things were better than status quo.  The feelings that I desperately need my husbands support have dwindled and my ability to hang on has strengthened. I still have a bad feeling that something is going to happen to me, but I guess that is just “memorial” jitters. You see this week is the week that my cancer  returned with a vengeance. It took us until Christmas that same year to figure it out, because I was pregnant I assumed many of the symptoms were related to pregnancy. 

boo

boo

Migraine headaches for starters as I recall.

So a good let it all out sobbing session was in order to clear my mind of my paranoid, nervous thinking. What it I fall and I have no help around me. What if I pass out while shopping with my little girl? So yesterday I was grateful to have not one but 2 helpers in my house. One to start and one to train.  I still have to call back more babysitters, because my husband and I have made a plan to go out one night a week to feel more partnership and time to just talk.  That was the result of our meeting with the shrink.  The other result is to explain better to my doctor about my lack of patience and my anxiousness. The not good enough meter or the knee jerk do something reactions are increasing as my stamina begins to fall apart.  I am hoping that the Doctor will understand my will to live is on an internal timer that ticks away at me every day and to just sit around a watch while my blood tumor markers starts to rise, makes me a slight bit ballistic / crazy.  I am a person of actions, much more than words. And when the doctor sees the result and casually says: now: the tumor is unrest. I personally have a hard time coping. Not only with the results but the nonchalant attitude. The dutch have a saying: Kat uit de boom kijken= watching the cat in the tree.  the meaning is we will watch to see if the solution IE the cat, can rectify itself. Thus let’s wait to see if the cat can climb down itself. I personally am feeling like that terrified cat, everyone is watching but no one is doing anything. And if I were the cat I would be meowing “Do Something”  Anything!

But I sit and I wait.  I wait for a new appointment, a new scan, a new chance to speak to my shrink. etc. etc.

vulnerability meter 8.5

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